On the estimation of sequestered parasite population in falciparum malaria patients

نویسندگان

  • Derdei Bichara
  • Nathalie Cozic
  • Abderrahman Iggidr
چکیده

The aim of this paper is to give an estimation of total parasitical burden of the patient and the rate of infection β in a malaria’s intra-host model by using control theory tools. Key-words: intra-host model, observers, estimation, Plasmodium falciparum, age-structured model ∗ Inria-Nancy Grand Est & University of Lorraine. LMAM(UMR CNRS 7122), Metz, France. On the estimation of sequestered parasite population in falciparum malaria patients Résumé : L’objectif de ce papier est de donner une estimation de la charge parasitaire totale d’un patient à partir de sa charge parasitaire périphérique. On donne aussi une méthode d’estimation du taux d’infection β dans un modèle intra-hôte du paludisme en utilisant les outils de la théorie du contrôle. Mots-clés : modèles intra-hôte, observateurs, estimation, Plasmodium falciparum, modèles structurés en classes d’âge Estimation of sequestered parasite population 3

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تاریخ انتشار 2012